| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4968-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4968-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | TSPO/PBR Rabbit mAb |
|---|---|
| Accession (Primary) | P30536 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse |
| Calculated MW | |
| Calculated MW: 19 kDa; Observed MW: 19 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:100-1:1000; ICC/IF-1:200-1:1000; FC-1:50-1:200; IP-1:10-1:100 | |
| Purification | |
| Affinity Chromatography | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| TSPO, also named Peripheral-type benzodiazepine receptor (PBR), encodes the translocator protein, belonging to tryptophan-rich sensory protein family. The protein is mainly localized in the outer mitochondrial membrane and expressed in steroid-synthesizing tissues (PMID:32881658, PMID:1326278). TSPO is involved in the translocation of cholesterol from the outer to inner mitochondrial membrane (PMID:21119734). In response to injury, TSPO has a upregulated expression in the peripheral nervous system (PMID:32423330, PMID:23251719). TSPO is also as a biomarker in a non-invasive procedure including detecting the inflammation in the heart and atherosclerotic plaques (PMID:24402571). | |
Target Information: ( P30536 ) | |
| Name | TSPO |
| Gene ID | 706 |
| Other Names | |
| BZRP; DBI; IBP; MBR; mDRC; PBR; pk18; PKBS; PTBR; Translocator protein; translocator protein (18kDa); TSPO | |
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ADMEbio Team
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ADMEbio Team