| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2767-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2767-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Thrombomodulin Rabbit mAb |
|---|---|
| Accession (Primary) | P07204 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 60 kDa; Observed MW: 95 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:100-1:1000; ICC/IF-1:100-1:200; FC-1:20-1:50; IP-1:10-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice. | |
Target Information: ( P07204 ) | |
| Name | THBD |
| Gene ID | 7056 |
| Other Names | |
| CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM; AHUS 6; AHUS6; BDCA 3; | |
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ADMEbio Team
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ADMEbio Team