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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1750-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1750-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Transcription Termination Factor 2/TTF2 Rabbit mAb |
|---|---|
| Accession (Primary) | Q9UNY4 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 130 kDa; Observed MW: 130 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:100-1:200; ICC/IF-1:50-1:100; FC-1:50-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Transcription elongation is an key target for control of eukaryotic gene expression. After initiating from a promoter, the RNA polymerase II elongation complex is subjected to a block to elongation by the action of components of N-TEF (negative transcription elongation factor) [PMID: 9748214]. Transcription termination factor 2 (TTF2) is a DsDNA-dependent ATPase that acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. It also contribute to mitotic transcription repression, and involved in pre-mRNA splicing[PMID:15125840, 12927788]. | |
Target Information: ( Q9UNY4 ) | |
| Name | TTF2 |
| Gene ID | 8458 |
| Other Names | |
| HuF2; ZGRF6; F2 | |
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ADMEbio Team
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