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>   Home   >   Products   >   Primary Antibodies   >   Tuberin Rabbit mAb   

Tuberin Rabbit mAb

 
Catalog #
ABZ2432
Application
WB, IF, FC, IP, ICC, IHC-P
Uniprot Id
P49815
Reactivity
Human
Isotype
IgG
 
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  • Western blot analysis of Tuberin in Hela, A549, MCF-7, 293T lysates using Tuberin antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human hepatic carcinoma using Tuberin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ2432-100 2 weeks 100 µL $499.00
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ABZ2432-20 2 weeks 20 µL $149.00
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Product Overview

NameTuberin Rabbit mAb
Accession (Primary)P49815
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 201 kDa; Observed MW: 201 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC:1:20; ICC/IF-1:20; FC-1:200-1:1000; IP-1:20
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis.

Target Information: ( P49815 )

NameTSC2
Gene ID7249
Other Names
LAM; TSC4; PPP1R160; TSC2
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