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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0057-100 | 7 days | 100 µg | $330.00 |
Select product before adding to cart
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| VAG0057-500 | 7 days | 500 µg | $1,320.00 | |||
| VAG0057-1000 | 7 days | 1000 µg | $1,760.00 |
Product Overview | |
| Name | CMV Pp52 |
|---|---|
| Description | |
| Cytomegalo Virus Pp52 (UL44) Recombinant | |
| Introduction | |
| CMV belongs to the Betaherpesvirinae subfamily of Herpesviridae which includes herpes simplex virustypes 1 and 2, varicella-zoster virus, and Epstein-Barrvirus. The herpesviruses share a characteristic ability to remain latentover long periods. CMV is a double-stranded linear DNA virus with 162 hexagonal protein capsomeres surrounded by a lipid membrane. CMV has the largest genome of the herpes viruses, ranging from 230-240 kilobase pairs. Human CMV is composed of unique and inverted repeats that include the existence of 4 genome isomers caused by inversion of L-S genome components (class E). Replication may be divided into immediate early, delayed early, and late gene expression based on time of synthesis after infection. The DNA is replicated by rolling circles. In vitro, CMV replicates in human fibroblasts. | |
| Source | |
| Escherichia Coli. | |
| Formulation | |
| CMV PP65 protein solution is supplied in PBS. | |
| Stability | |
| CMV Pp65 protein although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| CMV Pp65 protein is >90% pure as determined by SDS-PAGE. | |
| Applications | |
| CMV Pp65 antigen is suitable for ELISA and Western blots, excellent antigen for detection of CMV with minimal specificity problems. | |
| Purification Method | |
| CMV Pp65 was purified by proprietary chromatographic technique. | |
| References | |
| Title: Cytomegalovirus-Infected Human Endothelial Cells Can Stimulate Allogeneic CD4+ Memory T Cells by Releasing Antigenic Exosomes Publication: Endocrinology 150.7 (2009): 3252-3258. Link: CMV Pp65 prospec publication | |
| Specificity | |
| Strongly reacts with human CMV positive serum. | |
| Precautions | |
| CMV Pp52 is for research use only and not for use in diagnostic or therapeutic procedures. | |
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ADMEbio Team
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ADMEbio Team
