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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0058-100 | 7 days | 100 µg | $330.00 |
Select product before adding to cart
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| VAG0058-500 | 7 days | 500 µg | $1,320.00 | |||
| VAG0058-1000 | 7 days | 1000 µg | $1,760.00 |
Product Overview | |
| Name | CMV Pp65 |
|---|---|
| Description | |
| Cytomegalo Virus Pp65 (UL83) Recombinant | |
| Introduction | |
| CMV is part of the Betaherpesvirinae subfamily of Herpesviridae; including herpes simplex virustypes 1 and 2, varicella-zoster virus, and Epstein-Barrvirus. The herpesviruses has the common ability to stay latentover long periods of time. CMV has the largest genome of the herpes viruses, ranging from 230-240 kilobase pairs. CMV is a double-stranded linear DNA virus with 162 hexagonal protein capsomeres surrounded by a lipid membrane. Human CMV is composed of unique and inverted repeats that include the existence of 4 genome isomers caused by inversion of L-S genome components (class E). Replication may be divided into immediate early, delayed early, and late gene expression based on time of synthesis after infection. The DNA is replicated by rolling circles. In vitro, CMV replicates in human fibroblasts. | |
| Source | |
| Escherichia Coli. | |
| Formulation | |
| 25mM Tris-Hcl pH 8, 8M Urea, 5mM bMe. | |
| Stability | |
| CMV Pp65 protein although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| CMV Pp65 protein is >95% pure as determined by SDS-PAGE. | |
| Applications | |
| CMV Pp65 antigen is suitable for ELISA and Western blots, excellent antigen for detection of CMV with minimal specificity problems. | |
| Purification Method | |
| CMV Pp65 was purified by proprietary chromatographic technique. | |
| References | |
| Title: Cytomegalovirus-Infected Human Endothelial Cells Can Stimulate Allogeneic CD4+ Memory T Cells by Releasing Antigenic Exosomes Publication: Endocrinology 150.7 (2009): 3252-3258. Link: CMV Pp65.prospec publication | |
| Specificity | |
| Immunoreactive with sera of CMV-infected individuals. | |
| Precautions | |
| CMV Pp65 is for research use only and not for use in diagnostic or therapeutic procedures. | |
References |
Title: Cytomegalovirus-Infected Human Endothelial Cells Can Stimulate Allogeneic CD4+ Memory T Cells by Releasing Antigenic Exosomes Publication: Endocrinology 150.7 (2009): 3252-3258. Link: CMV Pp65 prospec publication |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
