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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0093-2 | 7 days | 2 µg | $120.00 |
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| VAG0093-10 | 7 days | 10 µg | $290.00 | |||
| VAG0093-100 | 7 days | 100 µg | $1,440.00 |
Product Overview | |
| Name | CoV-2-S1 (319-541) |
|---|---|
| Description | |
| Coronavirus 2019 Spike Glycoprotein-S1 Receptor Binding Domain (319-541 a.a), Recombinant | |
| Accession (Primary) | QHD43416.1 |
| Introduction | |
| A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019. The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans. While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus. | |
| Source | |
| HEK293 Cells. | |
| Physical Appearance | |
| Lyophilized freezed dried powder. | |
| Formulation | |
| CoV-2 S1 RBD protein is lyophilized from 1x PBS pH-7.4 + 10% trehalose. | |
| Stability | |
| Lyophilized Cov-2 S1 Glycoprotein RBD although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CoV2 Spike protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Protein is >90% pure as determined SDS-PAGE. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized CoV-2 S1 protein in sterile 18M-cm H2O at a concentration of 0.2mg/ml and not less than 0.1mg/ml, which can then be further diluted to other aqueous solutions. | |
| Purification Method | |
| Purified by Metal-Afinity chromatographic technique. | |
| Precautions | |
| CoV-2-S1 (319-541) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( QHD43416.1 ) | |
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ADMEbio Team
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ADMEbio Team
