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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0178-100 | 7 days | 100 µg | $330.00 |
Select product before adding to cart
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| VAG0178-500 | 7 days | 500 µg | $1,320.00 | |||
| VAG0178-1000 | 7 days | 1000 µg | $1,760.00 |
Product Overview | |
| Name | HAV VP3 |
|---|---|
| Description | |
| Hepatitis A Virus VP3 Recombinant | |
| Introduction | |
| Forty-two antigenic domains were identified across the hepatitis A virus (HAV) polyprotein by using a set of 237 overlapping 20-mer synthetic peptides spanning the entire HAV polyprotein. Nineteen antigenic domains were found within the structural proteins, and 22 were found within the nonstructural proteins, with 1 domain spanning the junction of VP1 and P2A proteins. Five of these domains were considered immunodominant, as judged by both the breadth and the strength of their immunoreactivity. One domain is located within the VP2 protein at position 57-90 aa. A second domain, located at position 767-842 aa, contains the C-terminal part of the VP1 protein and the entire P2A protein. A third domain, located at position 1403-1456 aa, comprises the C-terminal part of the P2C protein and the N-terminal half of the P3A protein. The fourth domain, located at position 1500-1519 aa, includes almost the entire P3B, and the last domain, located at position 1719-1764 aa, contains the C-terminal region of the P3C protein and the N-terminal region of the P3D protein. Four of the five most immunoreactive domains are derived from small HAV proteins and/or encompass protein cleavage sites separating different HAV proteins. | |
| Source | |
| Escherichia Coli. | |
| Formulation | |
| 10mM CBB, pH9.6, 0.1% SDS and 50% glycerol. | |
| Stability | |
| HAV VP4-VP2 protein although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| HAV VP4-VP2 protein is >90% pure as determined by 10% PAGE (coomassie staining). | |
| Applications | |
| HAV VP4-VP2 antigen is suitable for ELISA and Western blots, excellent antigen for detection of HAV with minimal specificity problems. | |
| Purification Method | |
| HAV VP4-VP2 Protein was purified by proprietary chromatographic technique. | |
| Specificity | |
| Immunoreactive with sera HAV-infected individuals. | |
| Precautions | |
| HAV VP3 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
