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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0198-100 | 7 days | 100 µg | $330.00 |
Select product before adding to cart
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| VAG0198-500 | 7 days | 500 µg | $1,320.00 | |||
| VAG0198-1000 | 7 days | 1000 µg | $1,760.00 |
Product Overview | |
| Name | HBV core (1-186) |
|---|---|
| Description | |
| Hepatitis B Virus Core (1-186 a.a.) Recombinant | |
| Introduction | |
| Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA. | |
| Formulation | |
| 7.5mM Phosphate buffer pH-7.2, 75mM NaCl, & 50% glycerol. | |
| Stability | |
| HBV Core Delta protein although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| HBV Core Delta protein is >95% pure as determined by SDS-PAGE (coomassie staining). | |
| Amino acid sequence | |
| MDIDPYKEFG ATVELLSFLP SDFFPSVRDL LDNASALYRE ALESPEHCSP HHTALRQAIL CWGELMTLAT WVGGNLEDPI SRDLVVSYVN TNMGLKFRQL LWFHISCLTF GRETVIEYLV SFGVWIRTPP AYRPPNAPIL S | |
| Applications | |
| HBV Core Delta antigen is suitable for ELISA and Western blots, excellent antigen for detection of HBV with minimal specificity problems. | |
| Purification Method | |
| Purified by proprietary chromatographic technique. | |
| Specificity | |
| Immunoreactive with sera HBV-infected individuals. | |
| Precautions | |
| HBV core (1-186) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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Thank you,
ADMEbio Team
