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HBV HBe

Hepatitis B Virus HBe Recombinant

 
Catalog #
VAG0200
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
VAG0200-100 7 days 100 µg $330.00
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VAG0200-500 7 days 500 µg $1,320.00
VAG0200-1000 7 days 1000 µg $1,760.00
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Product Overview

NameHBV HBe
Description
Hepatitis B Virus HBe Recombinant
Introduction
Hepatitis B virus surface gene encodes 3 proteins: small (HBs), middle (MHBs) and large (LHBs) surface protein. These 3 proteins are translated from distinct start codons, however share a common reading frame and stop codon. HBs contains 226 amino acids, it is a major viral envelope component. MHBs has extra 55 amino acids (Pre-S2) located to the N-terminus of HBs, LHBs has an additional 119 amino acids (Pre-S1). Pre-S is a region is comprised of Pre-S1 and S2, Pre-S1 has a vital role in receptor recognition, while Pre-S2 plays a part in translocation of virus into host cell. Clinically, HBV pre-S is linked with HBsAg and HBV DNA copies, which indicates active replication of virus, reduction of pre-S is typically associated with decreased HBV DNA copies, pointing to an improved predictor of treatment. In addition, Pre-S is a potential vaccine under development to enhance currently used HBsAg vaccine.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered solution.
Formulation
Sterile Filtered solution containing PBS, and 25mM K2CO3.
Stability
HBV Pre-S although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purity
Protein is >95% pure as determined by 12% PAGE (coomassie staining).
Applications
Immunoassay.
Purification Method
Purified by proprietary chromatographic technique.
Precautions
HBV HBe is for research use only and not for use in diagnostic or therapeutic procedures.
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