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HCV Core 16.8kDa

Hepatitis C Virus Nucleocapsid (core) 16.8kDa Recombinant

 
Catalog #
VAG0211
 
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Product Overview

NameHCV Core 16.8kDa
Description
Hepatitis C Virus Nucleocapsid (core) 16.8kDa Recombinant
Introduction
HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
Sterile filtered solution containing Phosphate saline buffer, 25mM K2CO3 and 6M urea.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Precautions
HCV Core 16.8kDa is for research use only and not for use in diagnostic or therapeutic procedures.
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