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HCV Core 22kDa, FLSCN

Hepatitis C Virus Core 22kDa, FLSCN Recombinant

 
Catalog #
VAG0215
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
VAG0215-100 7 days 100 µg $500.00
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VAG0215-500 7 days 500 µg $1,800.00
VAG0215-1000 7 days 1000 µg $2,400.00
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Product Overview

NameHCV Core 22kDa, FLSCN
Description
Hepatitis C Virus Core 22kDa, FLSCN Recombinant
Introduction
HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Formulation
20mM Tris-Hcl pH 8, 8M urea and 10mM B-ME.
Stability
HCV-Core although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purity
HCV-Core protein is >95% pure as determined by 10% PAGE (coomassie staining).
Applications
HCV Core antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
Purification Method
HCV-Core protein was purified by proprietary chromatographic technique.
Specificity
Immunoreactive with sera of HCV-infected individuals.
Precautions
HCV Core 22kDa, FLSCN is for research use only and not for use in diagnostic or therapeutic procedures.
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