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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0237-100 | 7 days | 100 µg | $330.00 |
Select product before adding to cart
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| VAG0237-500 | 7 days | 500 µg | $1,320.00 | |||
| VAG0237-1000 | 7 days | 1000 µg | $2,160.00 |
Product Overview | |
| Name | HCV NS3 |
|---|---|
| Description | |
| Hepatitis C Virus NS3 (1450-1643 a.a.) Recombinant | |
| Introduction | |
| HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). | |
| Formulation | |
| 1.5M urea, 25mM Tris-HCl pH-8, 0.2% Triton-X & 50% Glycerol. | |
| Stability | |
| NS3 Genotype-1b although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| HCV NS3 Genotype-1b protein is >95% pure as determined by 10% PAGE (coomassie staining). | |
| Applications | |
| ELISA, Western blots and Flow-through. | |
| Purification Method | |
| HCV NS3 Genotype-1b protein was purified by proprietary chromatographic technique. | |
| Specificity | |
| Immunoreactive with sera of HCV-infected individuals. | |
| Precautions | |
| HCV NS3 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
