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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0257-100 | 7 days | 100 µg | $330.00 |
Select product before adding to cart
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| VAG0257-500 | 7 days | 500 µg | $1,320.00 | |||
| VAG0257-1000 | 7 days | 1000 µg | $2,160.00 |
Product Overview | |
| Name | HCV NS3 Genotype-6a |
|---|---|
| Description | |
| Hepatitis C Virus NS3 Genotype-6a, (1192-1459 a.a.) Recombinant | |
| Introduction | |
| HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host''s immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). | |
| Formulation | |
| HCV NS3 in 20mM Tris-HCl pH-8, 1mM DTT & 10% Glycerol. | |
| Stability | |
| HCV-NS3 His although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| Protein is >95% pure as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGS VAHL HAPTGSGKST KVPAAYAAQG YKVLVLNPSV AATLGFGAYM SKAHGVDPNI RTGVRTITTG SPITYSTYGK FLADGGCSGG AYDIIICDEC HSTDATSILG IGTVLDQAET AGARLVVLAT ATPPGSVTVS HPNIEEVALS TTGEIPFYGK AIPLEVIKGG RHLIFCHSKK KCDELAAKLV ALGINAVAYY RGLDVSVIPT SGDVVVVSTD ALMTGFTGDF DSVIDCNT. | |
| Precautions | |
| HCV NS3 Genotype-6a is for research use only and not for use in diagnostic or therapeutic procedures. | |
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ADMEbio Team
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