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HCV NS5, HRP

Hepatitis C Virus NS5, Horseradish Peroxidase Recombinant

 
Catalog #
VAG0288
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
VAG0288-100 7 days 100 µg $500.00
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VAG0288-500 7 days 500 µg $1,800.00
VAG0288-1000 7 days 1000 µg $2,400.00
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Product Overview

NameHCV NS5, HRP
Description
Hepatitis C Virus NS5, Horseradish Peroxidase Recombinant
Introduction
NS5A is a component of the replication complex which takes part in RNA-binding. NS5A protein’s hyperphosphorylated form is an inhibitor of viral replication. NS5A interacts with Human VAPB and through it targets the viral replication complex to vesicles. NS5A down-regulates viral IRES translation initiation and mediates interferon resistance by interacting and inhibiting human EIF2AK2/PKR. NS5a is also inhibits apoptosis by interacting with BIN1 and FKBP8.
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
The HCV NS5A protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 40% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH M SLKATCTAN HDSPDAELIE ANLLWRQEMG GNITRVESEN KVVILDSFDP LVAEEDEREV SVPAEILRKS RRFARALPVW ARPDYNPPLV ETWKKPDY.
Precautions
HCV NS5, HRP is for research use only and not for use in diagnostic or therapeutic procedures.
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