Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0289-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
|
||
| VAG0289-10 | 7 days | 10 µg | $290.00 | |||
| VAG0289-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | HCV NS5A |
|---|---|
| Description | |
| Hepatitis C Virus NS5A Recombinant | |
| Accession (Primary) | P27958 |
| Introduction | |
| HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). | |
| Formulation | |
| 1.5M urea, 25mM Tris-HCl pH 8.0, 0.2% Triton-X and 50% Glycerol. | |
| Stability | |
| HCV NS5B although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| Protein is >95% pure as determined by SDS-PAGE. | |
| Applications | |
| HCV NS5B antigen in ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems. | |
| Purification Method | |
| HCV NS5B Genotype-1b protein was purified by proprietary chromatographic technique. | |
| Specificity | |
| Immunoreactive with sera of HCV-infected individuals. | |
| Precautions | |
| HCV NS5A is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P27958 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
