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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0321-100 | 7 days | 100 µg | $330.00 |
Select product before adding to cart
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| VAG0321-500 | 7 days | 500 µg | $1,320.00 | |||
| VAG0321-1000 | 7 days | 1000 µg | $2,160.00 |
Product Overview | |
| Name | HIV-1 nef |
|---|---|
| Description | |
| HIV-1 nef Recombinant | |
| Introduction | |
| HIV-1 Nef is anessential factor for efficient viral replication and pathogenesis and therefore is produced shortly after virus infection. HIV-1 Nef is also facilitates virus replication and enhances virions infectivity. Nef exerts pleiotropic effects: decreases cell surface CD4 antigen by interacting with the Src family kinase LCK, down-modulates surface MHC-I molecules and protects the infected cell from apoptosis in order to keep it alive until the next virus generation is mature. Nef protein bypasses host T-cell signaling byinducing a trascriptional program almost identical to that of anti-CD3 cell activation. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| HIV-1 nef Biotin protein solution containing PBS & 0.05%(v/v) glycerol. | |
| Stability | |
| HIV-1 nef Biotin although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Applications | |
| Western Blotting, SDS Page | |
| Precautions | |
| HIV-1 nef is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
