Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0338-1 | 7 days | 1 µg | $120.00 |
Select product before adding to cart
|
||
| VAG0338-5 | 7 days | 5 µg | $290.00 | |||
| VAG0338-50 | 7 days | 50 µg | $1,600.00 |
Product Overview | |
| Name | HIV-1 TAT Clade-B, Biotin |
|---|---|
| Description | |
| HIV-1 TAT Clade-B Recombinant, Biotin Labeled | |
| Accession (Primary) | P69697.1 |
| Introduction | |
| Human immunodeficiency virus type-1 (HIV-1) regulatory Tat protein plays an essential role in viral replication and infectivity. In addition, during acute infection, Tat is released extracellularly by infected cells and is taken up by neighboring cells where it transactivates viral replication and increases virus infectivity. HIV-1 Tat activates transcription of HIV-1 viral genes by inducing phosphorylation of the C-terminal domain (CTD) of RNA polymerase II (RNAPII). Tat can also disturb cellular metabolism by inhibiting proliferation of antigen-specific T lymphocytes and by inducing cellular apoptosis. Tat-induced apoptosis of T-cells is attributed, in part, to the distortion of microtubules polymerization. LIS1 is a microtubule-associated protein that facilitates microtubule polymerization. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless clear solution. | |
| Formulation | |
| 0.1% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Precautions | |
| HIV-1 TAT Clade-B, Biotin is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P69697.1 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
