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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0375-100 | 7 days | 100 µg | $330.00 |
Select product before adding to cart
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| VAG0375-500 | 7 days | 500 µg | $1,320.00 | |||
| VAG0375-1000 | 7 days | 1000 µg | $2,160.00 |
Product Overview | |
| Name | HTLV-1 gp46 mosaic |
|---|---|
| Description | |
| HTLV-I gp46 Mosaic Recombinant | |
| Introduction | |
| Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies). | |
| Formulation | |
| 20mM Phosphate buffer PH 7.5. | |
| Stability | |
| HTLV-1 Mosaic although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| Protein is >95% pure as determined by SDS-PAGE. | |
| Applications | |
| HTLV-1 Mosaic can be used as an antigen in ELISA and Western Blots. Excellent reagent for correct detection of HTLV infections, with minimal specificity problems. | |
| Purification Method | |
| HTLV-1 Mosaic was purified by proprietary chromatographic technique. | |
| Specificity | |
| Immunoreactive with sera of HTLV-I infected individuals | |
| Precautions | |
| HTLV-1 gp46 mosaic is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
