| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0376-100 | 7 days | 100 µg | $330.00 |
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| VAG0376-500 | 7 days | 500 µg | $1,320.00 | |||
| VAG0376-1000 | 7 days | 1000 µg | $2,160.00 |
Product Overview | |
| Name | HTLV-1 mosaic |
|---|---|
| Description | |
| HTLV-1 Mosaic Recombinant | |
| Introduction | |
| Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies). HTLV-1 p24 is usually used for clinical diagnosis and forms both monomer and dimer on SDS-PAGE gel but the majority of protein is a dimer. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| HTLV-1 p24 protein solution containing PBS, pH-7.4. | |
| Stability | |
| HTLV-1 p24 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| Protein is >95% pure as determined by 12% SDS-PAGE (coomassie staining). | |
| Precautions | |
| HTLV-1 mosaic is for research use only and not for use in diagnostic or therapeutic procedures. | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team