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HTLV-1 mosaic

HTLV-1 Mosaic Recombinant

 
Catalog #
VAG0376
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
VAG0376-100 7 days 100 µg $330.00
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VAG0376-500 7 days 500 µg $1,320.00
VAG0376-1000 7 days 1000 µg $2,160.00
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Product Overview

NameHTLV-1 mosaic
Description
HTLV-1 Mosaic Recombinant
Introduction
Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies). HTLV-1 p24 is usually used for clinical diagnosis and forms both monomer and dimer on SDS-PAGE gel but the majority of protein is a dimer.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
HTLV-1 p24 protein solution containing PBS, pH-7.4.
Stability
HTLV-1 p24 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purity
Protein is >95% pure as determined by 12% SDS-PAGE (coomassie staining).
Precautions
HTLV-1 mosaic is for research use only and not for use in diagnostic or therapeutic procedures.
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