| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0377-100 | 7 days | 100 µg | $330.00 |
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| VAG0377-500 | 7 days | 500 µg | $1,320.00 | |||
| VAG0377-1000 | 7 days | 1000 µg | $2,160.00 |
Product Overview | |
| Name | HTLV-1 p24 |
|---|---|
| Description | |
| HTLV-1 p24 Recombinant | |
| Introduction | |
| Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies). | |
| Formulation | |
| 10mM NaPO4 pH 6.0, containing 1mM DTT & 1mM EDTA. | |
| Stability | |
| HTLV-1 p24 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| HTLV-1 p24 protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC. | |
| Applications | |
| HTLV-1 p24 antigen can be used for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems. | |
| Purification Method | |
| HTLV-1 p24 was purified by proprietary chromatographic technique. | |
| Specificity | |
| Immunoreactive with all sera of HTLV-1 infected individuals. | |
| Precautions | |
| HTLV-1 p24 is for research use only and not for use in diagnostic or therapeutic procedures. | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team