| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0453-2 | 7 days | 2 µg | $120.00 |
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| VAG0453-10 | 7 days | 10 µg | $290.00 | |||
| VAG0453-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | SARS Spike (306-515) |
|---|---|
| Description | |
| Coronavirus Spike Receptor Binding Domain (306-515 a.a.), Recombinant | |
| Accession (Primary) | P59594 |
| Synonyms | |
| Spike glycoprotein, S glycoprotein, Peplomer protein, E2 glycoprotein precursor, Severe acute repiratory Syndrome-related Coronavirus, SARS, SRAS-CoV, SARS-CoV1, E2. | |
| Introduction | |
| SARS Coronavirus is an enveloped virus containing 3 outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein takes part in virus infection cycle and is the primary target of neutralizing antibodies. | |
| Source | |
| Sf9, Baculovirus cells. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The SARS Spike (306-515) solution (0.5mg/ml) contains Phosphate-Buffered Saline (pH 7.4) and 10% Glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| ADP RVVPSGD VVRFPNITNL CPFGEVFNAT KFPSVYAWER KKISNCVADY SVLYNSTFFS TFKCYGVSAT KLNDLCFSNV YADSFVVKGD DVRQIAPGQT GVIADYNYKL PDDFMGCVLA WNTRNIDATS TGNYNYKYRY LRHGKLRPFE RDISNVPFSP DGKPCTPPAL NCYWPLNDYG FYTTTGIGYQ PYRVVVLSFE LLNAPATVCG PKL HHHHHH | |
| Biological Activity | |
| Measured by its binding ability in a functional ELISA with Human ACE-2 (CAT# enz-1159). | |
| Precautions | |
| SARS Spike (306-515) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P59594 ) | |
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ADMEbio Team
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ADMEbio Team