Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| VAG0495-100 | 7 days | 100 µg | $400.00 |
Select product before adding to cart
|
||
| VAG0495-500 | 7 days | 500 µg | $1,600.00 | |||
| VAG0495-1000 | 7 days | 1000 µg | $2,240.00 |
Product Overview | |
| Name | Trypanosoma Cruzi B13 |
|---|---|
| Description | |
| Trypanosoma Cruzi B13 Recombinant | |
| Accession (Primary) | Q7YZF5 |
| Introduction | |
| Trypsin is a serine protease that hydrolyses proteins, it is found in the digestive system of numerous vertebrates. Trypsin is produced as the inactive proenzyme trypsinogen in the pancreas. Trypsin cleaves peptide chains at the carboxyl side of the amino acids lysine and arginine, except when either is followed by proline. Trypsin is secreted into the duodenum, where it acts to hydrolyses peptides into amino acids, which is necessary for the uptake of protein in the food even though peptides are smaller than proteins; they are still too big to be absorbed through the lining of the ileum. The optimal operating pH for Trypsins is about 8 and about 37°C temperature. In cystic fibrosis disease there is a deficiency in transport of trypsin and other digestive enzymes from the pancreas. Trypsin is widely used in various biotechnological processes since it’s available in high quantity in the pancreases, and can be purified rather easily. | |
| Source | |
| Corn. | |
| Physical Appearance | |
| Sterile Filtered lyophilized powder. | |
| Formulation | |
| The protein was lyophilized without any additives. | |
| Stability | |
| Store the Bovine Trypsin between 2-8°C, do not freeze. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Biological Activity | |
| 4,313 Units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Bovine Trypsin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| Trypanosoma Cruzi B13 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q7YZF5 ) | |
Background |
Among the numerous antigens that T. cruzi expresses, the B13 protein has been identified as a main component involved in immune recognition and host-parasite interactions. Trypanosoma Cruzi B13 is a very immunogenic antigen found in the T. cruzi epimastigote and trypomastigote forms. Trypanosoma Cruzi B13 takes part in host-parasite interactions first by binding to host cells such as cardiac and smooth muscle cells, which are very important in the pathology of Chagas disease. Trypanosoma cruzi is the protozoan parasite responsible for Chagas disease which affects millions of people in Latin America. The parasite has a complex life cycle and eludes the immune response through various mechanisms, making it a complex target for therapeutic interventions. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
