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Dengue Rapid Test

Dengue Antigen for Rapid Test Recombinant

 
Catalog #
VAG0515
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
VAG0515-100 7 days 100 µg $300.00
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VAG0515-500 7 days 500 µg $1,200.00
VAG0515-1 7 days 1 mg $1,920.00
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Product Overview

NameDengue Rapid Test
Description
Dengue Antigen for Rapid Test Recombinant
Synonyms
Dickkopf-related protein 1, Dickkopf-1, Dkk-1, hDkk-1, SK, DKK1, dickkopf WNT signaling pathway inhibitor 1, Dickkopf 1 Homolog, Dickkopf Related Protein-1, Dickkopf-1 Like, Dickkopf-Like Protein 1, Dickkopf (Xenopus Laevis) Homolog 1, DKK-1.
Introduction
Dickkopf-related protein 1 (DKK1) antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by creating a ternary complex with the transmembrane protein KREMEN which promotes internalization of LRP5/6. DKKs have a significant role in vertebrate development, where they locally inhibit Wnt controlled processes for instance antero-posterior axial patterning, limb development, somitogenesis and eye formation. Furthermore, Dkks are involved in bone formation and bone disease, cancer and Alzheimer disease in Adults.
Source
HEK.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
The DKK1 protein was lyophilized from solution containing 1x PBS, pH 7.4 .
Stability
Lyophilized DKK1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution DKK1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity
Greater than 97.0% as determined by analysis by SDS-PAGE and HPLC analysis.
Amino acid sequence
TLNSVLNSN IKNLPPPLGG AAGHPGSAVS AAPGILYPGG NKYQTIDNYQ PYPCAEDEEC GTDEYCASPT RGGDAGVQIC LACRKRRKRC MRHAMCCPGN YCKNGICVSS DQNHFRGEIE ETITESFGND HSTLDGYSRR TTLSSKMYHT KGQEGSVCLR SSDCASGLCC ARHFWSKICK PVLKEGQVCT KHRRKGSHGL EIFQRCYCGE GLSCRIQKDH HQASNSSRLH TCQRH.
Biological Activity
The specific activity was determined by its ability to inhibit the proliferation of HCT116 colorectal carcinoma cells. Approximately 40% growth inhibition was achieved at a DKK-1 concentration of 200ng/ml.
Solubility
It is recommended to reconstitute the lyophilized DKK1 in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Precautions
Dengue Rapid Test is for research use only and not for use in diagnostic or therapeutic procedures.
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