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Influenza-A H1N1 New Caledonia

H1N1 Influenza-A Virus New Caledonia/20/99 Recombinant

 
Catalog #
VAG0540
Uniprot Id
DQ508857
 
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Product Overview

NameInfluenza-A H1N1 New Caledonia
Description
H1N1 Influenza-A Virus New Caledonia/20/99 Recombinant
Accession (Primary)DQ508857
Introduction
Influenza-B virus is a genus in the virusfamily Orthomyxoviridae. The only species in this genus is called "Influenza B virus". Influenza B virus only infects humansand seals. This limited host range is apparently in contrast with those caused by the similar Influenza virus Aas both mutate by both genetic drift and reassortment. Influenza-B virus evolves slower than A viruses and faster than C viruses. Influenza-B virus mutates at a rate 2-3 times lower than type A. However, influenza B mutates enough that lasting immunity is not possible. The Influenza B virus capsidis enveloped while its virionconsists of a matrix protein + envelope + nucleoprotein complex + nucleocapsid, and a polymerasecomplex. Influenza B is sometimes spherical and sometimes filamentous. Its 500 or so surface projections are made of hemagglutinin and neuraminidase. The Influenza B virus is 14648 nucleotideslong and consists of eight segments of linear negative-sense, single-stranded RNA. The multipartite genome is encapsidated, each segment in a separate nucleocapsid, and the nucleocapsids are surrounded by one envelope.
Source
Baculovirus Insect Cells.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The Recombinant B/Ohio/01/05 solution contains 30mM Sodium phosphate, pH 7.4 and 50mM NaCl.
Stability
B/Ohio/01/05 Recombinant should be stored at 4°C.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Immunological Activity
Western-Blot 0.1 µg -1 µg per strip, ELISA 1 µg/Well.
Precautions
Influenza-A H1N1 New Caledonia is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( DQ508857 )

References

Title : Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection Publication : The Rockefeller University Press , doi: 10.1084/jem.20101352 © 2011 Wrammert et al. Link : http://jem.rupress.org/content/early/2011/01/06/jem.20101352.full

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