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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ3228-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ3228-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Vinculin Rabbit mAb |
|---|---|
| Accession (Primary) | P18206 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 124 kDa; Observed MW: 124 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; ICC/IF-1:50-1:200; FC-1:100-1:200; IP-1:10-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short, flexible proline-rich region and a carboxy-terminal tail. In the inactive state, the head and tail domains of vinculin interact to form a closed confirmation. The open and active form of vinculin translocates to focal adhesions where it is thought to be involved in anchoring F-actin to the membrane and regulation of cell migration. | |
Target Information: ( P18206 ) | |
| Name | VCL |
| Gene ID | 7414 |
| Other Names | |
| VCL; Vinculin; Metavinculin; MV; MVCL; CMD1W; CMH15; HEL114; Epididymis luminal protein 114; | |
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ADMEbio Team
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