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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| NTR0002-5 | 5 µg | $60.00 |
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| NTR0002-20 | 20 µg | $100.00 | ||||
| NTR0002-1 | 1 mg | $1,584.00 |
Product Overview | |
| Name | b NGF Human |
|---|---|
| Description | |
| Beta Nerve Growth Factor Human Recombinant | |
| Accession (Primary) | P01138 |
| Synonyms | |
| Beta Polypeptide, NGF, NGFB, HSAN5, Beta-NGF, MGC161426, MGC161428. | |
| Introduction | |
| NGF-beta has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. | |
| Source | |
| HEK293 cells. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The b-NGF was lyophilized from 1mg/ml in 20mM PB and 0.25M NaCl pH-7.5. | |
| Stability | |
| Lyophilized b-NGF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution b-NGF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97% as obsereved by SDS-PAGE. | |
| Biological Activity | |
| The specific activity was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line), the ED 50 is < 0.04-0.4ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized b-NGF in sterile distilled pyrogen free water at a concentration of 0.25mg/ml. | |
| Precautions | |
| b NGF Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01138 ) | |
References |
Title: u-Opioid receptor activation in live cells Publication: Journal 22.10 (2008): 3537-3548. Link: b NGF prospec publication |
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ADMEbio Team
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ADMEbio Team
