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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| NTR0003-5 | 5 µg | $120.00 |
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| NTR0003-20 | 20 µg | $290.00 | ||||
| NTR0003-1 | 1 mg | $4,320.00 |
Product Overview | |
| Name | b NGF Human, HEK |
|---|---|
| Description | |
| beta Nerve Growth Factor Human Recombinant, HEK | |
| Accession (Primary) | P01138 |
| Synonyms | |
| Beta Polypeptide, NGF, NGFB, HSAN5, Beta-NGF, MGC161426, MGC161428. | |
| Introduction | |
| NGF-beta has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. | |
| Source | |
| Submaxillary Gland of Grown Mouse. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The NGF beta Mouse was lyophilized from solution containing 5% mannitol and 1% HSA. | |
| Stability | |
| Lyophilized Mouse Beta-NGF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Murine NGF-Beta should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE . | |
| Amino acid sequence | |
| SSTHPVFHMGEF SVCDSVSVWV GDKTTATDIK GKEVTVLAEV NINNSVFRQY FFETKCRASN PVESGCRGID SKHWNSYCTT THTFVKALTT DEKQAAWRFI RIDTACVCVL SRKATRRG. | |
| Biological Activity | |
| The method used to test the bioassay is the NGF-dependent survival of dorsal root ganglia neurons of chick embryo, corresponding to a Specific Activity of 500,000IU/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Murine NGF-beta in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| References | |
| V aron S, Raibo rn C. Dissociation, fractionation and culture ofchick embryo sympathetic ganglionic cells [ J ]. J N eu rocy tol, 1972; 1: 211- 221. | |
| Precautions | |
| b NGF Human, HEK is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01138 ) | |
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ADMEbio Team
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