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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ3955-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ3955-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | beta Arrestin 1 (6A1) Mouse mAb |
|---|---|
| Accession (Primary) | P49407 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 47 kDa; Observed MW: 51 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011] | |
Target Information: ( P49407 ) | |
| Name | ARRB1 |
| Gene ID | 408 |
| Other Names | |
| ARB1; ARR1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1. | |
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ADMEbio Team
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