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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1747-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1747-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | xCT Rabbit mAb |
|---|---|
| Accession (Primary) | Q9UPY5 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 55 kDa; Observed MW: 55 kDa | |
| Buffer System | |
| 1xPBS(pH 7.4), 150mM NaCl, 50% Glycerol, 0.02% Sodium azide and 0.05% BSA | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:4000; IF-1:50-1:200; IP-1:50 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. | |
Target Information: ( Q9UPY5 ) | |
| Name | SLC7A11 |
| Gene ID | 23657 |
| Other Names | |
| SLC7A11; CCBR1; Cysteine/glutamate transporter; solute carrier family 7 | |
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ADMEbio Team
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ADMEbio Team
