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>   Home   >   Products   >   Primary Antibodies   >   IFITM1 Rabbit mAb   

IFITM1 Rabbit mAb

 
Catalog #
ABZ3007
Application
WB, IF, FC, IP, ICC, IHC-F, IHC-P
Uniprot Id
P13164
Reactivity
Human
Isotype
IgG
 
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  • Immunocytochemistry analysis of IFITM1 (green) in K562 using IFITM1 antibody,and DAPI(blue).
  • Western blot analysis of IFITM1 in K562 lysates using IFITM1 antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using IFITM1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ3007-100 2 weeks 100 µL $499.00
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ABZ3007-20 2 weeks 20 µL $149.00
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Product Overview

NameIFITM1 Rabbit mAb
Accession (Primary)P13164
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 14 kDa; Observed MW: 14 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-P-1:200-1:2000; ICC/IF-1:200-1:500; FC-1:200-1:500; IP-1:20-1:50
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.

Target Information: ( P13164 )

NameIFITM1
Gene ID8519
Other Names
9-27; CD225; IFI17; LEU13; DSPA2a; CD225/IFITM1
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