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>   Home   >   Products   >   Primary Antibodies   >   hHR23B (5H1) Mouse mAb   

hHR23B (5H1) Mouse mAb

 
Catalog #
ABZ3939
Application
WB, IF, ICC, IHC-F, IHC-P
Uniprot Id
P54727
Reactivity
Human, Mouse, Rat, Cat, Hamster
Isotype
IgG2b
 
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  • Western blot analysis of hHR23b in A431, K562, Jurkat, C6, 3T3 and Hela lysates using hHR23b antibody.
  • Immunocytochemistry analysis of Rad23B (5H1) in HeLa using hHR23b antibody.
  • Immunohistochemistry analysis of paraffin-embedded Prostate Cancer using hHR23b antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Western blot analysis of Rad23B (5H1) in K562, SW480, CHO-K1, 3T3 and COS7 lysates using Rad23B (5H1) antibody
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ3939-100 2 weeks 100 µL $499.00
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ABZ3939-20 2 weeks 20 µL $149.00
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Product Overview

NamehHR23B (5H1) Mouse mAb
Accession (Primary)P54727
Host SpeciesMouse
ClonalityMonoclonal
IsotypeIgG2b
Species Reactivity
Reacts WithHuman, Mouse, Rat, Cat, Hamster
Calculated MW
Calculated MW: 43 kDa; Observed MW: 58 kDa
Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-1:50-1:100; IF-1:50-1:200
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Target Information: ( P54727 )

NameRAD23B
Gene ID5887
Other Names
Rad23B; RAD23B; UV excision repair protein RAD23 homolog B; HR23B; hHR23B; XP-C repair-complementing complex 58 kDa protein; p58
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