| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ3988-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ3988-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Cyclin D2 (6E11) Mouse mAb |
|---|---|
| Accession (Primary) | P30279 |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 33 kDa; Observed MW: 38 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition (PubMed:18827403, PubMed:8114739). Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase (PubMed:18827403, PubMed:8114739). | |
Target Information: ( P30279 ) | |
| Name | CCND2 |
| Gene ID | 894 |
| Other Names | |
| cyclin D2; G1/S-specific cyclin D2 | |
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ADMEbio Team
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ADMEbio Team