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ERK1/2 (1B4) Mouse mAb

Catalog #: ABZ3991
Application: WB, IHC-P
Uniprot Id: P27361
Reactivity: Human, Mouse, Rat
Isotype: IgG1

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Western blot analysis of ERK1/2 (1B4)in Hela lysates, mouse Brain lysates, rat Brain lysates using ERK1/2 antibody.
Immunohistochemistry analysis of paraffin-embedded Human Lung Carcinoma Tissue using ERK1/2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using ERK1/2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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	ABZ3991-20	2 weeks	20 µL	reduce add	$149.00	Add to Cart INQUIRE Select product before adding to cart

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Datasheet
Citations
Reviews

Species Reactivity
Product Overview
Name	ERK1/2 (1B4) Mouse mAb
Accession (Primary)	P27361
Host Species	Mouse
Clonality	Monoclonal
Isotype	IgG1
Reacts With	Human, Mouse, Rat
Calculated MW
Calculated MW: 44,42 kDa; Observed MW: 44,42 kDa
Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-1:50-1:100
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Target Information: ( P27361 )
Name	MAPK3/MAPK1
Gene ID	5595/5594
Other Names
MAPK3; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MAPK1; ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK.

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