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>   Home   >   Products   >   Primary Antibodies   >   Phospho-p27 KIP 1 (Ser10) Rabbit mAb   

Phospho-p27 KIP 1 (Ser10) Rabbit mAb

 
Catalog #
ABZ4400
Application
WB, IP, IHC-P
Uniprot Id
P46527
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of Phospho-p27 KIP 1 (Ser10) in Hela, 3T3 lysates using Phospho-p27 Kip 1 (Ser10) antibody.
  • Western blot analysis of Phospho-p27 KIP 1 (Ser10) in C6 lysates using Phospho-p27 KIP 1 (Ser10) antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human breast cancer using p27 KIP 1 (Phospho-Ser10) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ4400-100 2 weeks 100 µL $499.00
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ABZ4400-20 2 weeks 20 µL $149.00
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Product Overview

NamePhospho-p27 KIP 1 (Ser10) Rabbit mAb
Accession (Primary)P46527
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 22 kDa; Observed MW: 27 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:50-1:100; IP-1:20-1:50
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Phosphorylated
Form
Liquid
Background
The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

Target Information: ( P46527 )

NameCDKN1B
Gene ID1027
Other Names
CDKN1B; KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1
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