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[KO]Integrin alpha V Rabbit mAb

Catalog #: ABZ4706
Application: WB, IHC-P
Uniprot Id: P06756
Reactivity: Human, Mouse, Rat
Isotype: IgG

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Western blot analysis of Integrin alpha V in HeLa(WT) and Integrin alpha V-Knockout HeLa(KO) using Integrin alpha V antibody.
Western blot analysis of Integrin alpha V in C6, 3T3, Hela lysates using Integrin alpha V antibody.
Immunohistochemistry analysis of paraffin-embedded Human tonsil using Integrin alpha V antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Datasheet
Citations
Reviews

Species Reactivity
Product Overview
Name	[KO]Integrin alpha V Rabbit mAb
Accession (Primary)	P06756
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Reacts With	Human, Mouse, Rat
Calculated MW
Calculated MW: 116 kDa; Observed MW: 135 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-1:200-1:500
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Target Information: ( P06756 )
Name	ITGAV
Gene ID	3685
Other Names
ITGAV; MSK8; VNRA; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51

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