| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4962-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4962-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | STIP1/STI1 Rabbit mAb |
|---|---|
| Accession (Primary) | P31948 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 63 kDa; Observed MW: 63 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:200-1:1000; FC-1:20-1:50 | |
| Purification | |
| Affinity Chromatography | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]). | |
Target Information: ( P31948 ) | |
| Name | STIP1 |
| Gene ID | 10963 |
| Other Names | |
| Hop; P60; STI1; STI1L; STIP1; Stress induced phosphoprotein 1 | |
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